Serena is a Pokémon Performer hailing from the Kanto Region. She moved to Kalos when she was 5, and met her second childhood friend Riley Houston, her first being Ash Ketchum who she met at a summer camp the year before she moved to Kalos.
Serena is described as a lovely young lady, who values her friends, but has a love-hate relationship with Riley. The two have been described to act like siblings when they are together, and both pull no punches when the opportunity to insult or “bully” the other arrives, although it never is anything damaging and is all in good fun.
Serena made her first appearance in Chapter 2: Right by Your Side where she was shown waking up, before greeting her childhood friend, Riley Houston. The two shared some banter, before taking off to Aquacorde Town
Serena made her final appearance in Chapter 110: Alola Ash!